Succinate Dehydrogenase-Deficient Gastrointestinal Stromal Tumors: Small Steps Toward Personalized Medicine?

Various molecular triggers define heterogeneous subsets of gastrointestinal stromal tumors (GISTs), differing in clinical behavior and drug sensitivity. KIT/PDGFRA-wild-type GISTs, including those succinate dehydrogenase (SDH)-deficient, are overall unresponsive to the tyrosine kinase inhibitors com...

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Detalles Bibliográficos
Autores principales: Ravegnini, Gloria, Ricci, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463228/
https://www.ncbi.nlm.nih.gov/pubmed/31020269
http://dx.doi.org/10.1177/2516865719842534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463228/
https://www.ncbi.nlm.nih.gov/pubmed/31020269
http://dx.doi.org/10.1177/2516865719842534

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