Cancer Cells Invade Confined Microchannels via a Self-Directed Mesenchymal-to-Amoeboid Transition

[Image: see text] Cancer cell invasion through physical barriers in the extracellular matrix (ECM) requires a complex synergy of traction force against the ECM, mechanosensitive feedback, and subsequent cytoskeletal rearrangement. PDMS microchannels were used to investigate the transition from mesen...

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Detalles Bibliográficos
Autores principales: Holle, Andrew W., Govindan Kutty Devi, Neethu, Clar, Kim, Fan, Anthony, Saif, Taher, Kemkemer, Ralf, Spatz, Joachim P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463244/
https://www.ncbi.nlm.nih.gov/pubmed/30775927
http://dx.doi.org/10.1021/acs.nanolett.8b04720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463244/
https://www.ncbi.nlm.nih.gov/pubmed/30775927
http://dx.doi.org/10.1021/acs.nanolett.8b04720

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