Plant glutathione biosynthesis revisited: redox-mediated activation of glutamylcysteine ligase does not require homo-dimerization

Plant γ-glutamylcysteine ligase (GCL), catalyzing the first and tightly regulated step of glutathione (GSH) biosynthesis, is redox-activated via formation of an intramolecular disulfide bond. In vitro, redox-activation of recombinant GCL protein causes formation of homo-dimers. Here, we have investi...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Yingxue, Lenherr, Esther D., Gromes, Roland, Wang, Shanshan, Wirtz, Markus, Hell, Rüdiger, Peskan-Berghöfer, Tanja, Scheffzek, Klaus, Rausch, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463388/
https://www.ncbi.nlm.nih.gov/pubmed/30877193
http://dx.doi.org/10.1042/BCJ20190072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463388/
https://www.ncbi.nlm.nih.gov/pubmed/30877193
http://dx.doi.org/10.1042/BCJ20190072

Ejemplares similares