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Plant glutathione biosynthesis revisited: redox-mediated activation of glutamylcysteine ligase does not require homo-dimerization

Plant γ-glutamylcysteine ligase (GCL), catalyzing the first and tightly regulated step of glutathione (GSH) biosynthesis, is redox-activated via formation of an intramolecular disulfide bond. In vitro, redox-activation of recombinant GCL protein causes formation of homo-dimers. Here, we have investi...

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Detalles Bibliográficos
Autores principales:	Yang, Yingxue, Lenherr, Esther D., Gromes, Roland, Wang, Shanshan, Wirtz, Markus, Hell, Rüdiger, Peskan-Berghöfer, Tanja, Scheffzek, Klaus, Rausch, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463388/ https://www.ncbi.nlm.nih.gov/pubmed/30877193 http://dx.doi.org/10.1042/BCJ20190072

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