Mitochondrial oxidative stress impairs contractile function but paradoxically increases muscle mass via fibre branching

BACKGROUND: Excess reactive oxygen species (ROS) and muscle weakness occur in parallel in multiple pathological conditions. However, the causative role of skeletal muscle mitochondrial ROS (mtROS) on neuromuscular junction (NMJ) morphology and function and muscle weakness has not been directly inves...

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Detalles Bibliográficos
Autores principales: Ahn, Bumsoo, Ranjit, Rojina, Premkumar, Pavithra, Pharaoh, Gavin, Piekarz, Katarzyna M., Matsuzaki, Satoshi, Claflin, Dennis R., Riddle, Kaitlyn, Judge, Jennifer, Bhaskaran, Shylesh, Satara Natarajan, Kavithalakshmi, Barboza, Erika, Wronowski, Benjamin, Kinter, Michael, Humphries, Kenneth M., Griffin, Timothy M., Freeman, Willard M., Richardson, Arlan, Brooks, Susan V., Van Remmen, Holly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463475/
https://www.ncbi.nlm.nih.gov/pubmed/30706998
http://dx.doi.org/10.1002/jcsm.12375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463475/
https://www.ncbi.nlm.nih.gov/pubmed/30706998
http://dx.doi.org/10.1002/jcsm.12375

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