Neurodegeneration and contralateral α-synuclein induction after intracerebral α-synuclein injections in the anterior olfactory nucleus of a Parkinson’s disease A53T mouse model

Parkinson’s disease is characterized by a proteinopathy that includes aggregates of α-synuclein. A recent hypothesis proposes a prion-like spreading mechanism for this α-synucleinopathy. Early neuropathological deposits occur, among others, in the anterior olfactory nucleus (AON). This study investi...

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Detalles Bibliográficos
Autores principales: Flores-Cuadrado, Alicia, Saiz-Sanchez, Daniel, Mohedano-Moriano, Alicia, Martinez-Marcos, Alino, Ubeda-Bañon, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463651/
https://www.ncbi.nlm.nih.gov/pubmed/30987677
http://dx.doi.org/10.1186/s40478-019-0713-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463651/
https://www.ncbi.nlm.nih.gov/pubmed/30987677
http://dx.doi.org/10.1186/s40478-019-0713-7

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