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Neurodegeneration and contralateral α-synuclein induction after intracerebral α-synuclein injections in the anterior olfactory nucleus of a Parkinson’s disease A53T mouse model
Parkinson’s disease is characterized by a proteinopathy that includes aggregates of α-synuclein. A recent hypothesis proposes a prion-like spreading mechanism for this α-synucleinopathy. Early neuropathological deposits occur, among others, in the anterior olfactory nucleus (AON). This study investi...
Autores principales: | Flores-Cuadrado, Alicia, Saiz-Sanchez, Daniel, Mohedano-Moriano, Alicia, Martinez-Marcos, Alino, Ubeda-Bañon, Isabel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463651/ https://www.ncbi.nlm.nih.gov/pubmed/30987677 http://dx.doi.org/10.1186/s40478-019-0713-7 |
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