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Aggregation of Microtubule Binding Repeats of Tau Protein is Promoted by Cu(2+)

[Image: see text] Understanding the factors that give rise to tau aggregation and reactive oxygen species (ROS) is the key aspect in Alzheimer’s disease pathogenesis. Microtubule (MT) binding repeats of tau protein were suggested to play a critical role in tau aggregation. Here, we show that the int...

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Detalles Bibliográficos
Autores principales: Ahmadi, Soha, Zhu, Shaolong, Sharma, Renu, Wu, Bing, Soong, Ronald, Dutta Majumdar, R., Wilson, Derek J., Simpson, Andre J., Kraatz, Heinz-Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463671/
https://www.ncbi.nlm.nih.gov/pubmed/31001602
http://dx.doi.org/10.1021/acsomega.8b03595