Panax ginseng Inhibits Metabolism of Diester Alkaloids by Downregulating CYP3A4 Enzyme Activity via the Pregnane X Receptor

To investigate the effects of P. ginseng C.A. Mey (P. ginseng) on the metabolism of diester alkaloids and explore the potential mechanism. P. ginseng was administered orally to rats for 7 days, after which liver microsome samples were prepared and then incubated with diester alkaloids. Ultra-high pe...

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Detalles Bibliográficos
Autores principales: Yang, Liang, Wang, Yuguang, Xu, Huanhua, Huang, Guangyao, Zhang, Zhaoyan, Ma, Zengchun, Gao, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463675/
https://www.ncbi.nlm.nih.gov/pubmed/31057647
http://dx.doi.org/10.1155/2019/3508658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463675/
https://www.ncbi.nlm.nih.gov/pubmed/31057647
http://dx.doi.org/10.1155/2019/3508658

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