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Panax ginseng Inhibits Metabolism of Diester Alkaloids by Downregulating CYP3A4 Enzyme Activity via the Pregnane X Receptor
To investigate the effects of P. ginseng C.A. Mey (P. ginseng) on the metabolism of diester alkaloids and explore the potential mechanism. P. ginseng was administered orally to rats for 7 days, after which liver microsome samples were prepared and then incubated with diester alkaloids. Ultra-high pe...
Autores principales: | Yang, Liang, Wang, Yuguang, Xu, Huanhua, Huang, Guangyao, Zhang, Zhaoyan, Ma, Zengchun, Gao, Yue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463675/ https://www.ncbi.nlm.nih.gov/pubmed/31057647 http://dx.doi.org/10.1155/2019/3508658 |
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