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NO-independent regulatory site of direct sGC stimulators like YC-1 and BAY 41-2272
BACKGROUND: The most important receptor for nitic oxide is the soluble guanylate cyclase (sGC), a heme containing heterodimer. Recently, a pyrazolopyridine derivative BAY 41-2272, structurally related to YC-1, was identified stimulating soluble guanylate cyclase in an NO-independent manner, which re...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC64637/ https://www.ncbi.nlm.nih.gov/pubmed/11801189 http://dx.doi.org/10.1186/1471-2210-1-13 |