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Novel prognostic markers within the CD44‐stromal ligand network in pancreatic cancer
The dense stroma in pancreatic cancer tumours is rich in secreted extracellular matrix proteins and proteoglycans. Secreted hyaluronan, osteopontin and type IV collagen sustain oncogenic signalling by interactions with CD44s and its variant isoform CD44v6 on cancer cell membranes. Although well esta...
Autores principales: | Franklin, Oskar, Billing, Ola, Öhlund, Daniel, Berglund, Anette, Herdenberg, Carl, Wang, Wanzhong, Hellman, Urban, Sund, Malin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463864/ https://www.ncbi.nlm.nih.gov/pubmed/30456933 http://dx.doi.org/10.1002/cjp2.122 |
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