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Dual blockage of STAT3 and ERK1/2 eliminates radioresistant GBM cells

Radiotherapy (RT) is the major modality for control of glioblastoma multiforme (GBM), the most aggressive brain tumor in adults with poor prognosis and low patient survival rate. To improve the RT efficacy on GBM, the mechanism causing tumor adaptive radioresistance which leads to the failure of tum...

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Detalles Bibliográficos
Autores principales: Xie, Bowen, Zhang, Lu, Hu, Wenfeng, Fan, Ming, Jiang, Nian, Duan, Yumei, Jing, Di, Xiao, Wenwu, Fragoso, Ruben C., Lam, Kit S., Sun, Lun-Quan, Li, Jian Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463934/
https://www.ncbi.nlm.nih.gov/pubmed/30986607
http://dx.doi.org/10.1016/j.redox.2019.101189