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Correction of gene model annotations improves isoform abundance estimates: the example of ketohexokinase ( Khk)

Next generation sequencing protocols such as RNA-seq have made the genome-wide characterization of the transcriptome a crucial part of many research projects in biology. Analyses of the resulting data provide key information on gene expression and in certain cases on exon or isoform usage. The emerg...

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Detalles Bibliográficos
Autores principales: Chabbert, Christophe D., Eberhart, Tanja, Guccini, Ilaria, Krek, Wilhelm, Kovacs, Werner J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464065/
https://www.ncbi.nlm.nih.gov/pubmed/31001414
http://dx.doi.org/10.12688/f1000research.17082.2