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PTGDR expression is upregulated through retinoic acid receptors (RAR) mechanism in allergy

Functional studies suggest that promoter polymorphisms of the Prostaglandin D Receptor (PTGDR) gene can be involved in asthma. All-trans Retinoic acid (ATRA) has also been linked to allergic diseases. We have previously described the PTGDR promoter activation mediated by ATRA through response elemen...

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Detalles Bibliográficos
Autores principales: García-Sánchez, Asunción, Marcos-Vadillo, Elena, Sanz, Catalina, Estravís, Miguel, Isidoro-García, María, Dávila, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464170/
https://www.ncbi.nlm.nih.gov/pubmed/30986261
http://dx.doi.org/10.1371/journal.pone.0215086