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Heavy-atom labeling of RNA by PLOR for de novo crystallographic phasing

Due to the paucity of known RNA structures, experimental phasing is crucial for obtaining three-dimensional structures of RNAs by X-ray crystallography. Covalent attachment of heavy atoms to RNAs is one of the most useful strategies to facilitate phase determination. However, this approach is limite...

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Detalles Bibliográficos
Autores principales: Stagno, Jason R., Yu, Ping, Dyba, Marzena A., Wang, Yun-Xing, Liu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464214/
https://www.ncbi.nlm.nih.gov/pubmed/30986270
http://dx.doi.org/10.1371/journal.pone.0215555