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Heavy-atom labeling of RNA by PLOR for de novo crystallographic phasing
Due to the paucity of known RNA structures, experimental phasing is crucial for obtaining three-dimensional structures of RNAs by X-ray crystallography. Covalent attachment of heavy atoms to RNAs is one of the most useful strategies to facilitate phase determination. However, this approach is limite...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464214/ https://www.ncbi.nlm.nih.gov/pubmed/30986270 http://dx.doi.org/10.1371/journal.pone.0215555 |