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Connexin 43 plays an important role in the transformation of cholangiocytes with Clonochis sinensis excretory-secretory protein and N-nitrosodimethylamine

BACKGROUND: Clonorchis sinensis is a group I bio-carcinogen responsible for cholangiocarcinoma (CHCA) in humans. However, the mechanism by which C. sinensis promotes carcinogenesis is unclear. METHODOLOGY: Using the human cholangiocyte line H69, we investigated cell proliferation and gap junction pr...

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Detalles Bibliográficos
Autores principales: Kim, Eun-Min, Bae, Young Mee, Choi, Min-Ho, Hong, Sung-Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464552/
https://www.ncbi.nlm.nih.gov/pubmed/30943209
http://dx.doi.org/10.1371/journal.pntd.0006843