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Dynamic repression by BCL6 controls the genome-wide liver response to fasting and steatosis

Transcription is tightly regulated to maintain energy homeostasis during periods of feeding or fasting, but the molecular factors that control these alternating gene programs are incompletely understood. Here, we find that the B cell lymphoma 6 (BCL6) repressor is enriched in the fed state and conve...

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Detalles Bibliográficos
Autores principales: Sommars, Meredith A, Ramachandran, Krithika, Senagolage, Madhavi D, Futtner, Christopher R, Germain, Derrik M, Allred, Amanda L, Omura, Yasuhiro, Bederman, Ilya R, Barish, Grant D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464608/
https://www.ncbi.nlm.nih.gov/pubmed/30983568
http://dx.doi.org/10.7554/eLife.43922