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Dynamic repression by BCL6 controls the genome-wide liver response to fasting and steatosis
Transcription is tightly regulated to maintain energy homeostasis during periods of feeding or fasting, but the molecular factors that control these alternating gene programs are incompletely understood. Here, we find that the B cell lymphoma 6 (BCL6) repressor is enriched in the fed state and conve...
Autores principales: | Sommars, Meredith A, Ramachandran, Krithika, Senagolage, Madhavi D, Futtner, Christopher R, Germain, Derrik M, Allred, Amanda L, Omura, Yasuhiro, Bederman, Ilya R, Barish, Grant D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464608/ https://www.ncbi.nlm.nih.gov/pubmed/30983568 http://dx.doi.org/10.7554/eLife.43922 |
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