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Developmental NMDA receptor dysregulation in the infantile neuronal ceroid lipofuscinosis mouse model
Protein palmitoylation and depalmitoylation alter protein function. This post-translational modification is critical for synaptic transmission and plasticity. Mutation of the depalmitoylating enzyme palmitoyl-protein thioesterase 1 (PPT1) causes infantile neuronal ceroid lipofuscinosis (CLN1), a ped...
Autores principales: | Koster, Kevin P, Francesconi, Walter, Berton, Fulvia, Alahmadi, Sami, Srinivas, Roshan, Yoshii, Akira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464704/ https://www.ncbi.nlm.nih.gov/pubmed/30946007 http://dx.doi.org/10.7554/eLife.40316 |
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