Developmental NMDA receptor dysregulation in the infantile neuronal ceroid lipofuscinosis mouse model

Protein palmitoylation and depalmitoylation alter protein function. This post-translational modification is critical for synaptic transmission and plasticity. Mutation of the depalmitoylating enzyme palmitoyl-protein thioesterase 1 (PPT1) causes infantile neuronal ceroid lipofuscinosis (CLN1), a ped...

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Detalles Bibliográficos
Autores principales: Koster, Kevin P, Francesconi, Walter, Berton, Fulvia, Alahmadi, Sami, Srinivas, Roshan, Yoshii, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464704/
https://www.ncbi.nlm.nih.gov/pubmed/30946007
http://dx.doi.org/10.7554/eLife.40316