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Unveiling novel targets of paclitaxel resistance by single molecule long-read RNA sequencing in breast cancer
RNA sequencing has become one of the most common technology to study transcriptomes in cancer, whereas its length limits its application on alternative splicing (AS) events and novel isoforms. Firstly, we applied single molecule long-read RNA sequencing (Iso-seq) and de novo assembly with short-read...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465246/ https://www.ncbi.nlm.nih.gov/pubmed/30988345 http://dx.doi.org/10.1038/s41598-019-42184-z |