Luteolin promotes apoptotic cell death via upregulation of Nrf2 expression by DNA demethylase and the interaction of Nrf2 with p53 in human colon cancer cells

Luteolin, a dietary flavone, modulates various signaling pathways involved in carcinogenesis. In this study, we investigated the molecular mechanism that underlies the apoptotic effects of luteolin mediated by DNA demethylation of the nuclear factor erythroid 2-related factor 2 (Nrf2) promoter and t...

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Detalles Bibliográficos
Autores principales: Kang, Kyoung Ah, Piao, Mei Jing, Hyun, Yu Jae, Zhen, Ao Xuan, Cho, Suk Ju, Ahn, Mee Jung, Yi, Joo Mi, Hyun, Jin Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465248/
https://www.ncbi.nlm.nih.gov/pubmed/30988303
http://dx.doi.org/10.1038/s12276-019-0238-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465248/
https://www.ncbi.nlm.nih.gov/pubmed/30988303
http://dx.doi.org/10.1038/s12276-019-0238-y

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