Development of a Phage Display Panning Strategy Utilizing Crude Antigens: Isolation of MERS-CoV Nucleoprotein human antibodies

Antibody phage display has been pivotal in the quest to generate human monoclonal antibodies for biomedical and research applications. Target antigen preparation is a main bottleneck associated with the panning process. This includes production complexity, downstream purification, quality and yield....

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Detalles Bibliográficos
Autores principales: Lim, Chia Chiu, Woo, Patrick C. Y., Lim, Theam Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465254/
https://www.ncbi.nlm.nih.gov/pubmed/30988390
http://dx.doi.org/10.1038/s41598-019-42628-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465254/
https://www.ncbi.nlm.nih.gov/pubmed/30988390
http://dx.doi.org/10.1038/s41598-019-42628-6

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