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Characterising side chains in large proteins by protonless (13)C-detected NMR spectroscopy
Side chains cover protein surfaces and are fundamental to processes as diverse as substrate recognition, protein folding and enzyme catalysis. However, characterisation of side-chain motions has so far been restricted to small proteins and methyl-bearing side chains. Here we present a class of metho...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465260/ https://www.ncbi.nlm.nih.gov/pubmed/30988305 http://dx.doi.org/10.1038/s41467-019-09743-4 |