Automated cell-based luminescence assay for profiling antiviral compound activity against enteroviruses

We describe the development, optimisation, and validation of an automated, cell-based and high-throughput screening assay using existing luminescence-based ATPlite reagents for identifying antiviral compounds that inhibit enterovirus replication. Antiviral efficacy was determined by measuring the AT...

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Detalles Bibliográficos
Autores principales: Zhang, Mingyu, Zhang, Yong, Wang, Yan, Lv, Wanyu, Zhang, Yanyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465263/
https://www.ncbi.nlm.nih.gov/pubmed/30988314
http://dx.doi.org/10.1038/s41598-019-42160-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465263/
https://www.ncbi.nlm.nih.gov/pubmed/30988314
http://dx.doi.org/10.1038/s41598-019-42160-7

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