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Dysregulation of Neuronal Gαo Signaling by Graphene Oxide in Nematode Caenorhabditis elegans

Exposure to graphene oxide (GO) induced some dysregulated microRNAs (miRNAs), such as the increase in mir-247, in nematode Caenorhabditis elegans. We here further identified goa-1 encoding a Gαo and pkc-1 encoding a serine/threonine protein kinase as the targets of neuronal mir-247 in the regulation...

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Detalles Bibliográficos
Autores principales: Liu, Peidang, Shao, Huimin, Ding, Xuecheng, Yang, Ruilong, Rui, Qi, Wang, Dayong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465305/
https://www.ncbi.nlm.nih.gov/pubmed/30988375
http://dx.doi.org/10.1038/s41598-019-42603-1