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Mechanism of the electroneutral sodium/proton antiporter PaNhaP from transition-path shooting
Na(+)/H(+) antiporters exchange sodium ions and protons on opposite sides of lipid membranes. The electroneutral Na(+)/H(+) antiporter NhaP from archaea Pyrococcus abyssi (PaNhaP) is a functional homolog of the human Na(+)/H(+) exchanger NHE1, which is an important drug target. Here we resolve the N...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465308/ https://www.ncbi.nlm.nih.gov/pubmed/30988359 http://dx.doi.org/10.1038/s41467-019-09739-0 |