Cargando…

Single cell RNA-sequencing identified Dec2 as a suppressive factor for spermatogonial differentiation by inhibiting Sohlh1 expression

Gonocyte-to-spermatogonia transition is a critical fate determination process to initiate sperm production throughout the lifecycle. However, the molecular dynamics of this process has not been fully elucidated mainly due to the asynchronized differentiation stages of neonatal germ cells. In this st...

Descripción completa

Detalles Bibliográficos
Autores principales: Makino, Yoshinori, Jensen, Niels H., Yokota, Naoko, Rossner, Moritz J., Akiyama, Haruhiko, Shirahige, Katsuhiko, Okada, Yuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465314/
https://www.ncbi.nlm.nih.gov/pubmed/30988352
http://dx.doi.org/10.1038/s41598-019-42578-z