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Single cell RNA-sequencing identified Dec2 as a suppressive factor for spermatogonial differentiation by inhibiting Sohlh1 expression
Gonocyte-to-spermatogonia transition is a critical fate determination process to initiate sperm production throughout the lifecycle. However, the molecular dynamics of this process has not been fully elucidated mainly due to the asynchronized differentiation stages of neonatal germ cells. In this st...
Autores principales: | Makino, Yoshinori, Jensen, Niels H., Yokota, Naoko, Rossner, Moritz J., Akiyama, Haruhiko, Shirahige, Katsuhiko, Okada, Yuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465314/ https://www.ncbi.nlm.nih.gov/pubmed/30988352 http://dx.doi.org/10.1038/s41598-019-42578-z |
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