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Early life stress disrupts intestinal homeostasis via NGF-TrkA signaling

Early childhood is a critical period for development, and early life stress may increase the risk of gastrointestinal diseases including irritable bowel syndrome (IBS). In rodents, neonatal maternal separation (NMS) induces bowel dysfunctions that resemble IBS. However, the underlying mechanisms rem...

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Detalles Bibliográficos
Autores principales: Wong, Hoi Leong Xavier, Qin, Hong-yan, Tsang, Siu Wai, Zuo, Xiao, Che, Sijia, Chow, Chi Fung Willis, Li, Xi, Xiao, Hai-tao, Zhao, Ling, Huang, Tao, Lin, Cheng Yuan, Kwan, Hiu Yee, Yang, Tao, Longo, Frank M., Lyu, Aiping, Bian, Zhao-xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465335/
https://www.ncbi.nlm.nih.gov/pubmed/30988299
http://dx.doi.org/10.1038/s41467-019-09744-3