miR-4521-FAM129A axial regulation on ccRCC progression through TIMP-1/MMP2/MMP9 and MDM2/p53/Bcl2/Bax pathways

Clear cell renal cell carcinoma (ccRCC) is the most aggressive RCC subtype with high metastasis, chemotherapy and radiotherapy resistance, and poor prognosis. This study attempted to establish the deregulations of miR-4521 and FAM129A together with their correlation to and mechanism of regulation of...

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Detalles Bibliográficos
Autores principales: Feng, Xue, Yan, Naimeng, Sun, Weibin, Zheng, Shanliang, Jiang, Sixiong, Wang, Jinxia, Guo, Chunmei, Hao, Lihong, Tian, Yuxiang, Liu, Shuqing, Sun, Ming-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465337/
https://www.ncbi.nlm.nih.gov/pubmed/31016032
http://dx.doi.org/10.1038/s41420-019-0167-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465337/
https://www.ncbi.nlm.nih.gov/pubmed/31016032
http://dx.doi.org/10.1038/s41420-019-0167-5

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