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Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp

The splenic white pulp is underpinned by poorly characterized stromal cells that demarcate distinct immune cell microenvironments. Here we establish fibroblastic reticular cell (FRC)-specific fate-mapping in mice to define their embryonic origin and differentiation trajectories. Our data show that a...

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Detalles Bibliográficos
Autores principales: Cheng, Hung-Wei, Onder, Lucas, Novkovic, Mario, Soneson, Charlotte, Lütge, Mechthild, Pikor, Natalia, Scandella, Elke, Robinson, Mark D., Miyazaki, Jun-ichi, Tersteegen, Anne, Sorg, Ursula, Pfeffer, Klaus, Rülicke, Thomas, Hehlgans, Thomas, Ludewig, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465367/
https://www.ncbi.nlm.nih.gov/pubmed/30988302
http://dx.doi.org/10.1038/s41467-019-09728-3