Cargando…

Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp

The splenic white pulp is underpinned by poorly characterized stromal cells that demarcate distinct immune cell microenvironments. Here we establish fibroblastic reticular cell (FRC)-specific fate-mapping in mice to define their embryonic origin and differentiation trajectories. Our data show that a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheng, Hung-Wei, Onder, Lucas, Novkovic, Mario, Soneson, Charlotte, Lütge, Mechthild, Pikor, Natalia, Scandella, Elke, Robinson, Mark D., Miyazaki, Jun-ichi, Tersteegen, Anne, Sorg, Ursula, Pfeffer, Klaus, Rülicke, Thomas, Hehlgans, Thomas, Ludewig, Burkhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465367/ https://www.ncbi.nlm.nih.gov/pubmed/30988302 http://dx.doi.org/10.1038/s41467-019-09728-3

Ejemplares similares

Intestinal fibroblastic reticular cell niches control innate lymphoid cell homeostasis and function
por: Cheng, Hung-Wei, et al.
Publicado: (2022)

Differentiation and activation of fibroblastic reticular cells
por: Lütge, Mechthild, et al.
Publicado: (2021)

Maturation of Lymph Node Fibroblastic Reticular Cells from Myofibroblastic Precursors Is Critical for Antiviral Immunity
por: Chai, Qian, et al.
Publicado: (2013)

Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality
por: Novkovic, Mario, et al.
Publicado: (2016)

PI16(+) reticular cells in human palatine tonsils govern T cell activity in distinct subepithelial niches
por: De Martin, Angelina, et al.
Publicado: (2023)

Fibroblastic reticular cell lineage convergence in Peyer’s patches governs intestinal immunity
por: Prados, Alejandro, et al.
Publicado: (2021)

Endothelial cell–specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation
por: Onder, Lucas, et al.
Publicado: (2013)

Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs
por: Gil-Cruz, Cristina, et al.
Publicado: (2016)

Remodeling of light and dark zone follicular dendritic cells governs germinal center responses
por: Pikor, Natalia B, et al.
Publicado: (2020)

A Novel Bacterial Artificial Chromosome-Transgenic Podoplanin–Cre Mouse Targets Lymphoid Organ Stromal Cells in vivo
por: Onder, Lucas, et al.
Publicado: (2011)

Conserved stromal–immune cell circuits secure B cell homeostasis and function
por: Lütge, Mechthild, et al.
Publicado: (2023)

PPARγ is essential for the development of bone marrow erythroblastic island macrophages and splenic red pulp macrophages
por: Okreglicka, Katarzyna, et al.
Publicado: (2021)

Adenovirus vector vaccination reprograms pulmonary fibroblastic niches to support protective inflating memory CD8(+) T cells
por: Cupovic, Jovana, et al.
Publicado: (2021)

B cell zone reticular cell microenvironments shape CXCL13 gradient formation
por: Cosgrove, Jason, et al.
Publicado: (2020)

Integrative Computational Modeling of the Lymph Node Stromal Cell Landscape
por: Novkovic, Mario, et al.
Publicado: (2018)

Fibroblastic reticular cells at the nexus of innate and adaptive immune responses
por: Perez‐Shibayama, Christian, et al.
Publicado: (2019)

Fibroblastic reticular cell-derived lysophosphatidic acid regulates confined intranodal T-cell motility
por: Takeda, Akira, et al.
Publicado: (2016)

Viral vector-mediated reprogramming of the fibroblastic tumor stroma sustains curative melanoma treatment
por: Ring, Sandra S., et al.
Publicado: (2021)

Central Nervous System Stromal Cells Control Local CD8(+) T Cell Responses during Virus-Induced Neuroinflammation
por: Cupovic, Jovana, et al.
Publicado: (2016)

B cell homeostasis and follicle confines are governed by fibroblastic reticular cells
por: Cremasco, Viviana, et al.
Publicado: (2014)

Insights into coronavirus immunity taught by the murine coronavirus
por: Grabherr, Sarah, et al.
Publicado: (2021)

Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis
por: Dubey, Lalit Kumar, et al.
Publicado: (2017)

Protective fibroblastic niches in secondary lymphoid organs
por: De Martin, Angelina, et al.
Publicado: (2023)

Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness
por: Boesch, Maximilian, et al.
Publicado: (2018)

Exploring human splenic red pulp vasculature in virtual reality: details of sheathed capillaries and the open capillary network
por: Steiniger, Birte S., et al.
Publicado: (2020)

The CLEC-2–podoplanin axis controls fibroblastic reticular cell contractility and lymph node microarchitecture
por: Astarita, Jillian L., et al.
Publicado: (2014)

YAP/TAZ direct commitment and maturation of lymph node fibroblastic reticular cells
por: Choi, Sung Yong, et al.
Publicado: (2020)

Lymphotoxin β Receptor: a Crucial Role in Innate and Adaptive Immune Responses against Toxoplasma gondii
por: Tersteegen, Anne, et al.
Publicado: (2021)

Integrin-dependence of Lymphocyte Entry into the Splenic White Pulp
por: Lo, Charles G., et al.
Publicado: (2003)

Reticular rash on the lower extremities
por: Thomas, Cristina, et al.
Publicado: (2018)

Reticular Diseases
Publicado: (2006)

Recent trends on the implementation of reticular materials in column‐centered separations
por: Fikarova, Katerina, et al.
Publicado: (2022)

Visualization and functional characterization of lymphoid organ fibroblasts
por: Onder, Lucas, et al.
Publicado: (2021)

The Genomics of Hairy Cell Leukaemia and Splenic Diffuse Red Pulp Lymphoma
por: Oscier, David, et al.
Publicado: (2022)

A rare case of splenic diffuse red pulp small B-cell lymphoma (SDRPL): a review of the literature on primary splenic lymphoma with hairy cells
por: Vig, Tanush, et al.
Publicado: (2018)

Spotlight on reticular pseudodrusen
por: Rabiolo, Alessandro, et al.
Publicado: (2017)

Dense reticular pattern
por: Marchiori, Edson, et al.
Publicado: (2022)

On the reticular construction concept of covalent organic frameworks
por: Lukose, Binit, et al.
Publicado: (2010)

Tight control – decision-making during T cell–vascular endothelial cell interaction
por: Firner, Sonja, et al.
Publicado: (2012)

Expression of mucosal addressin cell adhesion molecule-1 on the reticular framework between white pulp and the marginal zone in the human spleen
por: Satoh, Takashi, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_unp1o0kf9j6re5vef1r2nnhmta