S-nitrosylation of the Peroxiredoxin-2 promotes S-nitrosoglutathione-mediated lung cancer cells apoptosis via AMPK-SIRT1 pathway

Protein S-nitrosylation, the redox-based posttranslational modification of a cysteine thiol by the attachment of a nitric oxide (NO) group, is responsible for a variety of signaling effects. Dysregulation of S-nitrosylation may be directly linked to cancer apoptotic resistance and cancer therapy out...

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Detalles Bibliográficos
Autores principales: Zhang, Yihan, Sun, Changning, Xiao, Guokai, Shan, Hui, Tang, Luyao, Yi, Yujiao, Yu, Wengong, Gu, Yuchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465399/
https://www.ncbi.nlm.nih.gov/pubmed/30988280
http://dx.doi.org/10.1038/s41419-019-1561-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465399/
https://www.ncbi.nlm.nih.gov/pubmed/30988280
http://dx.doi.org/10.1038/s41419-019-1561-x

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