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S-nitrosylation of the Peroxiredoxin-2 promotes S-nitrosoglutathione-mediated lung cancer cells apoptosis via AMPK-SIRT1 pathway
Protein S-nitrosylation, the redox-based posttranslational modification of a cysteine thiol by the attachment of a nitric oxide (NO) group, is responsible for a variety of signaling effects. Dysregulation of S-nitrosylation may be directly linked to cancer apoptotic resistance and cancer therapy out...
Autores principales: | Zhang, Yihan, Sun, Changning, Xiao, Guokai, Shan, Hui, Tang, Luyao, Yi, Yujiao, Yu, Wengong, Gu, Yuchao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465399/ https://www.ncbi.nlm.nih.gov/pubmed/30988280 http://dx.doi.org/10.1038/s41419-019-1561-x |
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