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Visualizing conformation transitions of the Lipid II flippase MurJ

The biosynthesis of many polysaccharides, including bacterial peptidoglycan and eukaryotic N-linked glycans, requires transport of lipid-linked oligosaccharide (LLO) precursors across the membrane by specialized flippases. MurJ is the flippase for the lipid-linked peptidoglycan precursor Lipid II, a...

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Detalles Bibliográficos
Autores principales: Kuk, Alvin C. Y., Hao, Aili, Guan, Ziqiang, Lee, Seok-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465408/
https://www.ncbi.nlm.nih.gov/pubmed/30988294
http://dx.doi.org/10.1038/s41467-019-09658-0