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Duloxetine, a Balanced Serotonin-Norepinephrine Reuptake Inhibitor, Improves Painful Chemotherapy-Induced Peripheral Neuropathy by Inhibiting Activation of p38 MAPK and NF-κB

Chemotherapy-induced peripheral neuropathy (CIPN) is a severe, toxic side effect that frequently occurs in anticancer treatment and may result in discontinuation of treatment as well as a serious reduction in life quality. The CIPN incidence rate is as high as 85–90%. Unfortunately, there is current...

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Detalles Bibliográficos
Autores principales: Meng, Jing, Zhang, Qiuyan, Yang, Chao, Xiao, Lu, Xue, Zhenzhen, Zhu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465602/
https://www.ncbi.nlm.nih.gov/pubmed/31024320
http://dx.doi.org/10.3389/fphar.2019.00365