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Methylation of HIF3A promoter CpG islands contributes to insulin resistance in gestational diabetes mellitus

BACKGROUND: Gestational diabetes mellitus (GDM) is defined as any degree of glucose intolerance during pregnancy, and will lead to high risk of diabetes even after pregnancy. Hypoxia‐inducible factor (HIF) family proteins are transcriptional factors that are highly correlated with methylation, which...

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Detalles Bibliográficos
Autores principales: Zhang, Yinghong, Chen, Yangyang, Qu, Hongmei, Wang, Yuanli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465726/
https://www.ncbi.nlm.nih.gov/pubmed/30743315
http://dx.doi.org/10.1002/mgg3.583