Efficacy-Based Perspective to Overcome Reduced Opioid Analgesia of Advanced Painful Diabetic Neuropathy in Rats

Reduction of the opioid analgesia in diabetic neuropathic pain (DNP) results from μ-opioid receptor (MOR) reserve reduction. Herein, we examined the antinociceptive and antiallodynic actions of a novel opioid agonist 14-O-methymorphine-6-O-sulfate (14-O-MeM6SU), fentanyl and morphine in rats with st...

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Detalles Bibliográficos
Autores principales: Balogh, Mihály, Zádor, Ferenc, Zádori, Zoltán S., Shaqura, Mohammed, Király, Kornél, Mohammadzadeh, Amir, Varga, Bence, Lázár, Bernadette, Mousa, Shaaban A., Hosztafi, Sándor, Riba, Pál, Benyhe, Sándor, Gyires, Klára, Schäfer, Michael, Fürst, Susanna, Al-Khrasani, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465774/
https://www.ncbi.nlm.nih.gov/pubmed/31024314
http://dx.doi.org/10.3389/fphar.2019.00347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465774/
https://www.ncbi.nlm.nih.gov/pubmed/31024314
http://dx.doi.org/10.3389/fphar.2019.00347

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