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An Allosteric Inhibitory Site Conserved in the Ectodomain of P2X Receptor Channels

P2X receptors constitute a gene family of cation channels gated by extracellular ATP. They mediate fast ionotropic purinergic signaling in neurons and non-excitable cell types in vertebrates. The highly calcium-permeable P2X4 subtype has been shown to play a significant role in cardiovascular physio...

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Detalles Bibliográficos
Autores principales: Ase, Ariel R., Therrien, Éric, Séguéla, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465887/
https://www.ncbi.nlm.nih.gov/pubmed/31024257
http://dx.doi.org/10.3389/fncel.2019.00121