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An Allosteric Inhibitory Site Conserved in the Ectodomain of P2X Receptor Channels
P2X receptors constitute a gene family of cation channels gated by extracellular ATP. They mediate fast ionotropic purinergic signaling in neurons and non-excitable cell types in vertebrates. The highly calcium-permeable P2X4 subtype has been shown to play a significant role in cardiovascular physio...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465887/ https://www.ncbi.nlm.nih.gov/pubmed/31024257 http://dx.doi.org/10.3389/fncel.2019.00121 |