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A Novel Mechanism of High Dose Radiation Sensitization by Metformin

Introduction: Metformin, the most widely used treatment for diabetes, is lethal to cancer cells and increases in toxicity when used in combination with radiation. In addition to various molecular and metabolic mechanisms that have been previously proposed, the studies presented provide evidence of a...

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Detalles Bibliográficos
Autores principales: Brown, Stephen L., Kolozsvary, Andrew, Isrow, Derek M., Al Feghali, Karine, Lapanowski, Karen, Jenrow, Kenneth A., Kim, Jae Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465931/
https://www.ncbi.nlm.nih.gov/pubmed/31024849
http://dx.doi.org/10.3389/fonc.2019.00247