Attenuation and Stability of CHIKV-NoLS, a Live-Attenuated Chikungunya Virus Vaccine Candidate

Our previous investigation of the nucleolar localisation sequence (NoLS) of chikungunya virus (CHIKV) capsid protein demonstrated the role of capsid in CHIKV virulence. Mutating the NoLS of capsid in CHIKV led to the development of a unique live-attenuated CHIKV vaccine candidate, termed CHIKV-NoLS....

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Detalles Bibliográficos
Autores principales: Abeyratne, Eranga, Freitas, Joseph R., Zaid, Ali, Mahalingam, Suresh, Taylor, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465992/
https://www.ncbi.nlm.nih.gov/pubmed/30583514
http://dx.doi.org/10.3390/vaccines7010002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465992/
https://www.ncbi.nlm.nih.gov/pubmed/30583514
http://dx.doi.org/10.3390/vaccines7010002

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