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Characterization of the Filovirus-Resistant Cell Line SH-SY5Y Reveals Redundant Role of Cell Surface Entry Factors

Filoviruses infect a wide range of cell types with the exception of lymphocytes. The intracellular proteins cathepsin B and L, two-pore channel 1 and 2, and bona fide receptor Niemann–Pick Disease C1 (NPC1) are essential for the endosomal phase of cell entry. However, earlier steps of filoviral infe...

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Detalles Bibliográficos
Autores principales: Zapatero-Belinchón, Francisco J., Dietzel, Erik, Dolnik, Olga, Döhner, Katinka, Costa, Rui, Hertel, Barbara, Veselkova, Barbora, Kirui, Jared, Klintworth, Anneke, Manns, Michael P., Pöhlmann, Stefan, Pietschmann, Thomas, Krey, Thomas, Ciesek, Sandra, Gerold, Gisa, Sodeik, Beate, Becker, Stephan, von Hahn, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466046/
https://www.ncbi.nlm.nih.gov/pubmed/30893855
http://dx.doi.org/10.3390/v11030275