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A Single V672F Substitution in the Spike Protein of Field-Isolated PEDV Promotes Cell–Cell Fusion and Replication in VeroE6 Cells

While porcine epidemic diarrhea virus (PEDV) infects and replicates in enterocytes lining villi of neonatal piglets with high efficiency, naturally isolated variants typically grow poorly in established cell lines, unless adapted by multiple passages. Cells infected with most cell-adapted PEDVs usua...

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Detalles Bibliográficos
Autores principales: Wanitchang, Asawin, Saenboonrueng, Janya, Kaewborisuth, Challika, Srisutthisamphan, Kanjana, Jongkaewwattana, Anan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466060/
https://www.ncbi.nlm.nih.gov/pubmed/30897856
http://dx.doi.org/10.3390/v11030282