Interferon-Independent Upregulation of Interferon-Stimulated Genes during Human Cytomegalovirus Infection is Dependent on IRF3 Expression

The antiviral activity of type I interferons (IFNs) is primarily mediated by interferon-stimulated genes (ISGs). Induction of ISG transcription is achieved when type I IFNs bind to their cognate receptor and activate the Janus Kinase/Signal Transducer and Activator of Transcription (JAK/STAT) signal...

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Detalles Bibliográficos
Autores principales: Ashley, Caroline L., Abendroth, Allison, McSharry, Brian P., Slobedman, Barry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466086/
https://www.ncbi.nlm.nih.gov/pubmed/30871003
http://dx.doi.org/10.3390/v11030246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466086/
https://www.ncbi.nlm.nih.gov/pubmed/30871003
http://dx.doi.org/10.3390/v11030246

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