A Diacylglycerol Kinase Inhibitor, R-59-022, Blocks Filovirus Internalization in Host Cells

Filoviruses, such as Ebola virus (EBOV) and Marburg virus, are causative agents of unpredictable outbreaks of severe hemorrhagic fevers in humans and non-human primates. For infection, filoviral particles need to be internalized and delivered to intracellular vesicles containing cathepsin proteases...

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Detalles Bibliográficos
Autores principales: Stewart, Corina M., Dorion, Stephanie S., Ottenbrite, Marie A. F., LeBlond, Nicholas D., Smith, Tyler K. T., Qiu, Shirley, Fullerton, Morgan D., Kobasa, Darwyn, Côté, Marceline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466206/
https://www.ncbi.nlm.nih.gov/pubmed/30832223
http://dx.doi.org/10.3390/v11030206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466206/
https://www.ncbi.nlm.nih.gov/pubmed/30832223
http://dx.doi.org/10.3390/v11030206

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