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Role of Type I Interferons on Filovirus Pathogenesis

Filoviruses, such as Ebola and Marburg virus, encode viral proteins with the ability to counteract the type I interferon (IFN-I) response. These IFN-I antagonist proteins are crucial to ensure virus replication, prevent an antiviral state in infected and bystander cells, and impair the ability of an...

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Detalles Bibliográficos
Autores principales: Escudero-Pérez, Beatriz, Muñoz-Fontela, César
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466283/
https://www.ncbi.nlm.nih.gov/pubmed/30791589
http://dx.doi.org/10.3390/vaccines7010022