Engineering Pathways in Central Carbon Metabolism Help to Increase Glycan Production and Improve N-Type Glycosylation of Recombinant Proteins in E. coli

Escherichia coli strains have been modified in a variety of ways to enhance the production of different recombinant proteins, targeting membrane protein expression, proteins with disulphide bonds, and more recently, proteins which require N-linked glycosylation. The addition of glycans to proteins r...

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Detalles Bibliográficos
Autores principales: Strutton, Benjamin, Jaffe, Stephen RP, Evans, Caroline A, Fowler, Gregory JS, Dobson, Paul D, Pandhal, Jagroop, Wright, Phillip C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466297/
https://www.ncbi.nlm.nih.gov/pubmed/30901908
http://dx.doi.org/10.3390/bioengineering6010027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466297/
https://www.ncbi.nlm.nih.gov/pubmed/30901908
http://dx.doi.org/10.3390/bioengineering6010027

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